The Breast
Volume 19, Issue 1 , Pages 44-49 , February 2010

Factors contributing to improved local control after mastectomy in patients with breast cancer aged 40 years or younger

  • Elke J.R. Lammers

      Affiliations

    • Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    • These authors contributed equally to this work.
  • ,
  • Paulien Huibers

      Affiliations

    • Faculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    • These authors contributed equally to this work.
  • ,
  • Maurice J.C. van der Sangen

      Affiliations

    • Department of Radiotherapy, Catharina Hospital, Eindhoven, The Netherlands
  • ,
  • Lonneke V. van de Poll-Franse

      Affiliations

    • Eindhoven Cancer Registry, Eindhoven, The Netherlands
    • CoRPS – Centre of Research on Psychology in Somatic Diseases, Department of Medical Psychology, Tilburg University, The Netherlands
  • ,
  • Philip M.P. Poortmans

      Affiliations

    • Department of Radiotherapy, Bernard Verbeeten Institute, Tilburg, The Netherlands
  • ,
  • Miranda F. Ernst

      Affiliations

    • Department of Surgery, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands
  • ,
  • Bea M.D. Lemaire

      Affiliations

    • Department of Surgery, Elkerliek Hospital, Helmond, The Netherlands
  • ,
  • Claartje M.E.M. Meijs

      Affiliations

    • Department of Surgery, St. Elisabeth Hospital, Tilburg, The Netherlands
  • ,
  • Hans K.S. Nuytinck

      Affiliations

    • Department of Surgery, Amphia Hospital, Breda, The Netherlands
  • ,
  • Adri C. Voogd

      Affiliations

    • Department of Epidemiology, Faculty of Health Medicine and Life Sciences, Research Institute Growth and Development (GROW) Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 43 3882387; fax: +31 43 3884128.

Received 30 June 2009 ,Revised 12 September 2009 ,Accepted 20 October 2009.

References 

  1. Siesling S, van der Aa MA, Coebergh JW, Pukkala E. Time–space trends in cancer incidence in The Netherlands in 1989–2003. Int J Cancer. 2008;122:2106–2114
  2. van Dongen JA, Voogd AC, Fentiman IS, et al. Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for research and treatment of cancer 10801 trial. J Natl Cancer Inst. 2000;92:1143–1150
  3. Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233–1241
  4. Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347:1227–1232
  5. van Nes JG, van de Velde CJ. The preferred treatment for young women with breast cancer – mastectomy versus breast conservation. Breast. 2006;15(Suppl. 2):S3–S10
  6. Ballinger RS, Mayer KF, Lawrence G, Fallowfield L. Patients' decision-making in a UK specialist centre with high mastectomy rates. Breast. 2008;17:574–579
  7. de la Rochefordiere A, Asselain B, Campana F, et al. Age as prognostic factor in premenopausal breast carcinoma. Lancet. 1993;341:1039–1043
  8. Vrieling C, Collette L, Fourquet A, et al. Can patient-, treatment- and pathology-related characteristics explain the high local recurrence rate following breast-conserving therapy in young patients?. Eur J Cancer. 2003;39:932–944
  9. Elkhuizen PH, van de Vijver MJ, Hermans J, Zonderland HM, van de Velde CJ, Leer JW. Local recurrence after breast-conserving therapy for invasive breast cancer: high incidence in young patients and association with poor survival. Int J Radiat Oncol Biol Phys. 1998;40:859–867
  10. Jobsen JJ, van der Palen J, Ong F, Meerwaldt JH. The value of a positive margin for invasive carcinoma in breast-conservative treatment in relation to local recurrence is limited to young women only. Int J Radiat Oncol Biol Phys. 2003;57:724–731
  11. Arriagada R, Le MG, Guinebretiere JM, Dunant A, Rochard F, Tursz T. Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients. Ann Oncol. 2003;14:1617–1622
  12. Voogd AC, Nielsen M, Peterse JL, et al. Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: pooled results of two large European randomized trials. J Clin Oncol. 2001;19:1688–1697
  13. Zhou P, Gautam S, Recht A. Factors affecting outcome for young women with early stage invasive breast cancer treated with breast-conserving therapy. Breast Cancer Res Treat. 2007;101:51–57
  14. Cabioglu N, Hunt KK, Buchholz TA, et al. Improving local control with breast-conserving therapy: a 27-year single-institution experience. Cancer. 2005;104:20–29
  15. van der Leest M, Evers L, van der Sangen MJ, et al. The safety of breast-conserving therapy in patients with breast cancer aged < or = 40 years. Cancer. 2007;109:1957–1964
  16. Bontenbal M, Nortier JW, Beex LV, et al. Adjuvant systemic therapy for patients with resectable breast cancer: guideline from the Dutch National Breast Cancer Platform and the Dutch Society for Medical Oncology. Ned Tijdschr Geneeskd. 2000;144:984–989
  17. Goldhirsch A, Glick JH, Gelber RD, Senn HJ. Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. J Natl Cancer Inst. 1998;90:1601–1608
  18. Goldhirsch A, Glick JH, Gelber RD, Coates AS, Senn HJ. Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. Seventh International Conference on Adjuvant Therapy of Primary Breast Cancer. J Clin Oncol. 2001;19:3817–3827
  19. Kievit W, Bolster MJ, van der Wilt GJ, et al. Cost-effectiveness of new guidelines for adjuvant systemic therapy for patients with primary breast cancer. Ann Oncol. 2005;16:1874–1881
  20. Coulombe G, Tyldesley S, Speers C, et al. Is mastectomy superior to breast-conserving treatment for young women?. Int J Radiat Oncol Biol Phys. 2007;67:1282–1290
  21. Park CC, Mitsumori M, Nixon A, et al. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J Clin Oncol. 2000;18:1668–1675
  22. Haffty BG, Wilmarth L, Wilson L, Fischer D, Beinfield M, McKhann C. Adjuvant systemic chemotherapy and hormonal therapy. Effect on local recurrence in the conservatively treated breast cancer patient. Cancer. 1994;73:2543–2548
  23. Levine MN, Bramwell V, Abu-Zahra H, et al. The effect of systemic adjuvant chemotherapy on local breast recurrence in node positive breast cancer patients treated by lumpectomy without radiation. Br J Cancer. 1992;65:130–132
  24. Buchholz TA, Tucker SL, Erwin J, et al. Impact of systemic treatment on local control for patients with lymph node-negative breast cancer treated with breast-conservation therapy. J Clin Oncol. 2001;19:2240–2246
  25. Ernst MF, Voogd AC, Coebergh JW, Poortmans PM, Roukema JA. Using loco-regional recurrence as an indicator of the quality of breast cancer treatment. Eur J Cancer. 2004;40:487–493
  26. Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366:2087–2106
  27. Overgaard M, Nielsen HM, Overgaard J. Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials. Radiother Oncol. 2007;82:247–253
  28. Ragaz J, Olivotto IA, Spinelli JJ, et al. Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst. 2005;97:116–126
  29. van Tienhoven G, Voogd AC, Peterse JL, et al. Prognosis after treatment for loco-regional recurrence after mastectomy or breast conserving therapy in two randomised trials (EORTC 10801 and DBCG-82TM). EORTC Breast Cancer Cooperative Group and the Danish Breast Cancer Cooperative Group. Eur J Cancer. 1999;35:32–38
  30. Bollet MA, Sigal-Zafrani B, Mazeau V, et al. Age remains the first prognostic factor for loco-regional breast cancer recurrence in young (<40 years) women treated with breast conserving surgery first. Radiother Oncol. 2007;82:272–280
  31. Jager JJ, Volovics L, Schouten LJ, et al. Loco-regional recurrences after mastectomy in breast cancer: prognostic factors and implications for postoperative irradiation. Radiother Oncol. 1999;50:267–275
  32. de Bock GH, van der Hage JA, Putter H, Bonnema J, Bartelink H, van de Velde CJ. Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy: long-term results of European Organisation for Research and Treatment of Cancer studies. Eur J Cancer. 2006;42:351–356

PII: S0960-9776(09)00138-6

doi: 10.1016/j.breast.2009.10.009

The Breast
Volume 19, Issue 1 , Pages 44-49 , February 2010