The Breast
Volume 19, Issue 2 , Pages 153-155 , April 2010

A vision to optimise the management of primary breast cancer in older women

  • K.L. Cheung

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44 (0)115 8231876; fax: +44 (0)115 8231877.

Received 28 September 2009 ,Accepted 27 January 2010.

References 

  1. Bartelink H, Horiot JC, Poortmans P, Struikmans H, Van den Bogaert W, Barillot I, et al. European Organization for Research and Treatment of Cancer Radiotherapy Breast Cancer Groups Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med. 2001;345:1378–1387
  2. Benhaim DI, Lopchinsky R, Tartter PI. Lumpectomy with tamoxifen as primary treatment for elderly women with early-stage breast cancer. Am J Surg. 2000;180:162–166
  3. Hughes KS, Schnaper LA, Berry D, Cirrincione C, McCormick B, Shank B, et al. Cancer and Leukemia Group B Radiation Therapy Oncology Group Eastern Cooperative Oncology Group Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med. 2004;351:971–977
  4. Hind D, Wyld L, Beverley CB, Reed MW. Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus). Cochrane Database Syst Rev. 2006;CD004272
  5. Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;365:1687–1717
  6. Siegelmann-Danieli N, Khandelwal V, Wood GC, Mainali R, Prichard J, Murphy TJ, et al. Breast cancer in elderly women: outcome as affected by age, tumor features, comorbidities, and treatment approach. Clin Breast Cancer. 2006;7:59–66
  7. Hurria A, Lichtman SM, Gardes J, Li D, Limaye S, Patil S, et al. Identifying vulnerable older adults with cancer: integrating geriatric assessment into oncology practice. J Am Gerontol Soc. 2007;55:1604–1608
  8. Valassiadou K, Morgan DAL, Robertson JFR, Pinder SE, Cheung KL. Successful management of elderly breast cancer patients treated without radiotherapy. World J Surg Oncol. 2007;5:62
  9. Cheung KL, Wong AWS, Parker H, Li VWY, Winterbottom L, Morgan DAL, et al. Pathological features of primary breast cancer in the elderly based on needle core biopsies – a large series from a single centre. Crit Rev Oncol Hematol. 2008;67:263–267[Epub 2008 June 3]
  10. Syed BM, Johnston SJ, Wong DWM, Morgan DAL, Ellis IO, Cheung KL. Surgery versus primary endocrine therapy for elderly women with oestrogen receptor positive early operable primary breast cancer – survival analysis and correlation with oestrogen receptor positivity. J Clin Oncol. 2009;27(15S):612;ASCO annual meeting proceedings I
  11. Al-Khyatt W, Syed BM, Morgan DAL, Cheung KL. Primary endocrine therapy for early operable primary breast cancer in elderly women – a large series from a single institution. J Clin Oncol. 2009;27(15S):630;ASCO annual meeting proceedings I
  12. Tang SW, Parker H, Winterbottom L, Hassell K, Ellis IO, Morgan DAL, et al. Early primary breast cancer in the elderly – pattern of presentation and treatment. Surg Oncol. 2009;Aug 11:[Epub ahead of print]
  13. Reed MW, Wyld L, Ellis P, Bliss J, Leonard R ACTION and ESTEeM Trial Management Groups. Breast cancer in older women: trials and tribulations. Clin Oncol (R Coll Radiol). 2009;21:99–102

PII: S0960-9776(10)00036-6

doi: 10.1016/j.breast.2010.01.019

The Breast
Volume 19, Issue 2 , Pages 153-155 , April 2010

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