The Breast
Volume 19, Issue 3 , Pages 157-158 , June 2010

Should fewer fractions be the new standard for postoperative radiotherapy in patients with early breast cancer?

References 

  1. Priestman TJ, Bullimore JA, Godden TP, Deutsch GP. The Royal College of Radiologists’ fractionation survey. Clinical Oncology. 1989;1(1):39–46
  2. Yarnold JR, Price P, Steel GG. Nonsurgical management of early breast cancer in the United Kingdom: radiotherapy fractionation practices. Clinical Audit Subcommittee of the Joint Council of Clinical Oncology. Clinical Oncology. 1995;7(4):223–226
  3. Delaney G, Blakey D, Drummond R, Kenny L, Rodger A on behalf of the Faculty of Radiation Oncology, Radiation Oncology Advisory Group to the National Breast Cancer Centre. Breast radiotherapy: an Australasian survey of current treatment techniques. Australasian Radiology. 2001;45:170–178
  4. Hawkes N. On the origin of variation. British Medical Journal. 2009;339:1284
  5. Owen JR, Ashton A, Bliss JM, Homewood J, Harper C, Hanson J, et al. Effect of radiotherapy fraction size on tumour control in patients with early breast cancer after local tumour excision: long-term results of a randomised trial. Lancet Oncology. 2006;7(6):467–471
  6. The START Trialists’ Group . The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for the treatment of early breast cancer: a randomised trial. Lancet Oncology. 2008;9(4):331–341
  7. The START Trialists’ Group . The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for the treatment of early breast cancer: a randomised trial. Lancet. 2008;371:1098–1107
  8. Whelan T, MacKenzie R, Julian J, Levine M, Shelley W, Grimard L, et al. Randomised trial of breast irradiation schedules after lumpectomy for lymph node- negative breast cancer. Journal of the National Cancer Institute. 2002;94(15):1143–1150
  9. NICE . Early and locally advanced breast cancer: diagnosis and treatment. Clinical guideline 80. London: NICE; 2009;
  10. Kamerow D. Yankee Doodling: mammograms, poor communication, politics. What lessons have been learnt from the US furore over new recommendations on breast screening?. British Medical Journal. 2009;339:1285
  11. Rodger A, Jack WJL, Kerr GR. A change in postmastectomy radiotherapy fractionation: an audit of tumour control, acute and late morbidity. The Breast. 1996;5:244–250
  12. Rodger A. Fears over radiotherapy fractionation regimens in breast cancer. Proposed UK trial needs to define techniques as well as numbers of treatments. British Medical Journal. 1998;317:155–156

PII: S0960-9776(10)00060-3

doi: 10.1016/j.breast.2010.03.006

The Breast
Volume 19, Issue 3 , Pages 157-158 , June 2010