The Breast
Volume 19, Issue 6 , Pages 479-483 , December 2010

Alcohol consumption and the risk of breast cancer among BRCA1 and BRCA2 mutation carriers

  • Jessica Dennis

      Affiliations

    • Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada
    • McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada
    • ,
  • Parviz Ghadirian

      Affiliations

    • McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada
    • Centre Hospitalier de l’Universitaire Montréal, CHUM Hôtel Dieu, Montreal, Canada
    • ,
  • Julian Little

      Affiliations

    • Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada
    • McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada
    • ,
  • Jan Lubinski

      Affiliations

    • Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland
    • ,
  • Jacek Gronwald

      Affiliations

    • Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland
    • ,
  • Charmaine Kim-Sing

      Affiliations

    • BC Cancer Agency, Vancouver, BC, Canada
    • ,
  • William Foulkes

      Affiliations

    • Departments of Medical Genetics and Oncology, McGill University, Canada
    • ,
  • Pal Moller

      Affiliations

    • Section of Cancer Genetics, Department of Medical Genetics, The National Hospital, Oslo, Norway
    • ,
  • Henry T. Lynch

      Affiliations

    • Department of Preventive Medicine and Public Health, Creighton University School of Medicine, Omaha, NE, USA
    • ,
  • Susan L. Neuhausen

      Affiliations

    • Department of Epidemiology, University of California at Irvine, Irvine, CA, USA
    • ,
  • Susan Domchek

      Affiliations

    • Abramson Cancer Center, University of Pennsylvania School of Medicine, USA
    • ,
  • Susan Armel

      Affiliations

    • Department of Obstetrics and Gynecology, University Health Network, Toronto, Ontario, Canada
    • ,
  • Claudine Isaacs

      Affiliations

    • Lombardi Cancer Center, Georgetown University Medical Center Georgetown, Washington, DC, USA
    • ,
  • Nadine Tung

      Affiliations

    • Beth Israel Deaconess Hospital, Boston, MA, Ohio, USA
    • ,
  • Kevin Sweet

      Affiliations

    • Division of Medical Genetics, Ohio State Medical Center, Columbus OH, USA
    • ,
  • Peter Ainsworth

      Affiliations

    • London Regional Cancer Program, London, Ontario, Canada
    • ,
  • Ping Sun

      Affiliations

    • Women’s College Research Institute, Women’s College Hospital and the University of Toronto, Canada
    • ,
  • Daniel Krewski

      Affiliations

    • Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada
    • McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada
    • ,
  • Steven Narod

      Affiliations

    • Women’s College Research Institute, Women’s College Hospital and the University of Toronto, Canada
    • Corresponding Author InformationCorresponding author at: Women’s College Research Institute, 790 Bay St., Toronto, Ontario M5G 1N8, Canada. Tel.: +1 416 351 3765.
    • ,
  • the Hereditary Breast Cancer Clinical Study Group

      Affiliations

    • Other members of the Hereditary Breast Cancer Clinical Study Group: Barry Rosen, Olufunmilayo Olopade, Fergus Couch, Ruth Gershoni-Baruch, Teresa Wagner, Howard Saal, Wendy Meschino, Amber Trivedi, Dawna Gilchrist, Charis Eng, Jeffrey Weitzel, Wendy McKinnon, Marie Wood, Barbara Pasini, Michael Osborne, Boris Pasche, Taya Fallen, Beth Karlan, Raluca N Kurz, Edmond Lemire, Jane Mclennan, Gareth Evans, Tomas Byrski, Tomas Huzarski, Lee Shulman, Eitan Friedman, Mary Daly, Judy Garber, Andrea Eisen, Louise Bordeleau, Carey Cullinane, Dana Zakalik, Ophira Ginsburg, Rochelle Demsky, Seema Panchal.

Received 10 March 2010 ,Revised 17 May 2010 ,Accepted 18 May 2010.

References 

  1. Antoniou A, Pharoah PD, Narod S, Risch HA, Eyfjord JE, Hopper JL, et al. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet. 2003;72:1117–1130
  2. Hamajima N, Hirose K, Tajima K, Rohan T, Calle EE, Heath CW, et al. Alcohol, tobacco and breast cancer-collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer. 2002;87:1234–1245
  3. Allen NE, Beral V, Casabonne D, Kan SW, Reeves GK, Brown A, et al. Moderate alcohol intake and cancer incidence in women. J Natl Cancer Inst. 2009 Mar 4;101(5):296–305
  4. Longnecker MP. Alcoholic beverage consumption in relation to risk of breast cancer: meta-analysis and review. Cancer Causes Control. 1994;5:73–82
  5. Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, et al. Alcohol and breast cancer in women: a pooled analysis of cohort studies. JAMA. 1998;279:535–540
  6. Zhang SM, Lee IM, Manson JE, Cook NR, Willett WC, Buring JE. Alcohol consumption and breast cancer risk in the Women’s Health Study. Am J Epidemiol. 2007;165:667–676
  7. Tjonneland A, Christensen J, Olsen A, Stripp C, Thomsen BL, Overvad K, et al. Alcohol intake and breast cancer risk: the European Prospective Investigation into Cancer and Nutrition (EPIC). Cancer Causes Control. 2007;18:361–373
  8. Ellison RC, Zhang Y, McLennan CE, Rothman KJ. Exploring the relation of alcohol consumption to risk of breast cancer. Am J Epidemiol. 2001;154:740–747
  9. McDonald JA, Mandel MG, Marchbanks PA, Folger SG, Daling JR, Ursin G, et al. Alcohol exposure and breast cancer: results of the women’s contraceptive and reproductive experiences study. Cancer Epidemiol Biomarkers Prev. 2004;13:2106–2116
  10. Kropp S, Becher H, Nieters A, Chang-Claude J. Low-to-moderate alcohol consumption and breast cancer risk by age 50 years among women in Germany. Am J Epidemiol. 2001;154:624–634
  11. Longnecker MP, Newcomb PA, Mittendorf R, Greenberg ER, Clapp RW, Bogdan GF, et al. Risk of breast cancer in relation to lifetime alcohol consumption. J Natl Cancer Inst. 1995;87:923–929
  12. Reichman ME, Judd JT, Longcope C, Schatzkin A, Clevidence BA, Nair PP, et al. Effects of alcohol consumption on plasma and urinary hormone concentrations in premenopausal women. J Natl Cancer Inst. 1993;85:722–727
  13. Rinaldi S, Peeters PH, Bezemer ID, Dossus L, Biessy C, Sacerdote C, et al. Relationship of alcohol intake and sex steroid concentrations in blood in pre- and post-menopausal women: the European Prospective Investigation into Cancer and Nutrition. Cancer Causes Control. 2006;17:1033–1043
  14. Dorgan JF, Baer DJ, Albert PS, Judd JT, Brown ED, Corle DK, et al. Serum hormones and the alcohol-breast cancer association in postmenopausal women. J Natl Cancer Inst. 2001;93:710–715
  15. Foulkes WD, Metcalfe K, Sun P, Hanna WM, Lynch HT, Ghadirian P, et al. Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type. Clin Cancer Res. 2004;10:2029–2034
  16. McGuire V, John EM, Felberg A, Haile RW, Boyd NF, Thomas DC, et al. No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages <50 years. Cancer Epidemiol Biomarkers Prev. 2006;15:1565–1567
  17. Bessaoud F, Daures JP. Patterns of alcohol (especially wine) consumption and breast cancer risk: a case-control study among a population in Southern France. Ann Epidemiol. 2008;18:467–475
  18. Newcomb PA, Nichols HB, Beasley JM, Egan K, Titus-Ernstoff L, Hampton JM, et al. No difference between red wine or white wine consumption and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2009;18:1007–1010
  19. Bianchini F, Vainio H. Wine and resveratrol: mechanisms of cancer prevention?. Eur J Cancer Prev. 2003;12:417–425
  20. Delmas D, Lancon A, Colin D, Jannin B, Latruffe N. Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer. Curr Drug Targets. 2006 Apr;7(4):423–442
  21. Burns J, Yokota T, Ashihara H, Lean ME, Crozier A. Plant foods and herbal sources of resveratrol. J Agric Food Chem. 2002;50:3337–3340
  22. Wang RH, Zheng Y, Kim HS, Xu X, Cao L, Luhasen T, et al. Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis. Mol Cell. 2008;32:11–20
  23. Le Corre L, Fustier P, Chalabi N, Bignon YJ, Bernard-Gallon D. Effects of resveratrol on the expression of a panel of genes interacting with the BRCA1 oncosuppressor in human breast cell lines. Clin Chim Acta. 2004;344:115–121
  24. Fustier P, Le Corre L, Chalabi N, Vissac-Sabatier C, Communal Y, Bignon YJ, et al. Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines. Br J Cancer. 2003;89:168–172
  25. Skeie G, Hjartaker A, Braaten T, Lund E. Dietary change among breast and colorectal cancer survivors and cancer-free women in the Norwegian Women and Cancer cohort study. Cancer Causes Control. 2009;[epub ahead of print]
  26. Holmes MD, Stampfer MJ, Colditz GA, Rosner B, Hunter DJ, Willett WC. Dietary factors and the survival of women with breast carcinoma. Cancer. 1999;86:826–835
  27. Dal Maso L, Zucchetto A, Talamini R, Serraino D, Stocco CF, Vercelli M, et al. Effect of obesity and other lifestyle factors on mortality in women with breast cancer. Int J Cancer. 2008;123:2188–2194

PII: S0960-9776(10)00141-4

doi: 10.1016/j.breast.2010.05.009

The Breast
Volume 19, Issue 6 , Pages 479-483 , December 2010

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