The Breast
Volume 20, Issue 1 , Pages 62-65 , February 2011

Intraoperative bone marrow puncture in breast cancer patients: Prospective assessment of adverse side-effects

  • Christoph Domschke

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 6221 5637330; fax: +49 6221 565233.
    • ,
  • Florian Neubrech

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany
    • ,
  • Michelle Dick

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany
    • ,
  • Joachim Rom

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany
    • ,
  • Philipp Beckhove

      Affiliations

    • Division of Translational Immunology, Tumor Immunology Program, German Cancer Research Center (DKFZ), INF 280, 69120 Heidelberg, Germany
    • ,
  • Christof Sohn

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany
    • ,
  • Florian Schuetz

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany
    • ,
  • Alexander Scharf

      Affiliations

    • Department of Gynecology and Obstetrics, University Hospital of Heidelberg, Voßstraße 9, 69115 Heidelberg, Germany

Received 31 December 2009 ,Revised 2 March 2010 ,Accepted 17 June 2010.

References 

  1. Bain BJ. Bone marrow biopsy morbidity and mortality: 2002 data. Clin Lab Haematol. 2004;26:315–318
  2. Bain BJ. Bone marrow biopsy morbidity: review of 2003. J Clin Pathol. 2005;58:406–408
  3. Bain BJ. Morbidity associated with bone marrow aspiration and trephine biopsy – a review of UK data for 2004. Haematologica. 2006;91:1293–1294
  4. Braun S, Pantel K, Müller P, Janni W, Hepp F, Kentenich CR, et al. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med. 2000;342:525–533
  5. Braun S, Vogl FD, Naume B, Janni W, Osborne MP, Coombes C, et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med. 2005;353:793–802
  6. Clare SE, Sener SF, Wilkens W, Goldschmidt R, Merkel D, Winchester DJ. Prognostic significance of occult lymph node metastases in node-negative breast cancer. Ann Surg Oncol. 1997;4:447–451
  7. Cote RJ, Rosen PP, Lesser ML, Old LJ, Osborne MP. Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastases. J Clin Oncol. 1991;9:1749–1756
  8. Devaliaf V, Tudor G. Bone marrow examination in obese patients. Br J Haematol. 2004;125:538–539
  9. Diel IJ, Kaufmann M, Costa SD, Holle R, von Minckwitz G, Solomayer EF, et al. Micrometastatic breast cancer cells in bone marrow at primary surgery – prognostic value in comparison to nodal status. J Natl Cancer Inst. 1996;88:1652–1658
  10. Diel IJ, Kaufmann M, Goerner R, Costa SD, Kaul S, Bastert G. Detection of tumor cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis. J Clin Oncol. 1992;10:1534–1539
  11. Gebauer G, Fehm T, Merkle E, Beck EP, Lang N, Jäger W. Epithelial cells in bone marrow of breast cancer patients at time of primary surgery: clinical outcome during long-term follow-up. J Clin Oncol. 2001;19:3669–3674
  12. Gerber B, Krause A, Müller H, Richter D, Reimer T, Makovitzky J, et al. Simultaneous immunohistochemical detection of tumor cells in lymph nodes and bone marrow aspirates in breast cancer and its correlation with other prognostic factors. J Clin Oncol. 2001;19:960–971
  13. Harbeck N, Untch M, Pache L, Eiermann W. Tumor cell detection in the bone marrow of breast cancer patients at primary therapy: results of a 3-year median follow-up. Br J Cancer. 1994;69:566–571
  14. Herr KA, Mobily PR. Comparison of selected pain assessment tools for use with the elderly. Appl Nurs Res. 1993;6:39–46
  15. Janni W, Rack B, Schindlbeck C, Strobl B, Rjosk D, Braun S, et al. The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence. Cancer. 2005;103:884–891
  16. Jensen MP, Karoly P, Braver S. The measurement of clinical pain intensity: a comparison of six methods. Pain. 1986;27:117–126
  17. Mansi JL, Easton D, Berger U, Gazet JC, Ford HT, Dearnaley D, et al. Bone marrow micrometastases in primary breast cancer: prognostic significance after 6 years follow-up. Eur J Cancer. 1991;27:1552–1555
  18. Naume B, Borgen E, Kvalheim G, Kåresen R, Qvist H, Sauer T, et al. Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: comparison with preoperative clinical parameters and primary tumor characteristics. Clin Cancer Res. 2001;7:4122–4129
  19. Pierga J-Y, Bonneton C, Vincent-Salomon A, de Cremoux P, Nos C, Blin N, et al. Clinical significance of immunocytochemical detection of tumor cells using digital microscopy in peripheral blood and bone marrow of breast cancer patients. Clin Cancer Res. 2004;10:1392–1400
  20. Scott J, Huskisson EC. Vertical or horizontal visual analogue scales. Ann Rheum Dis. 1979;38:560
  21. Solomayer EF, Diel IJ, Salanti G, Hahn M, Gollan C, Schütz F, et al. Time independence of the prognostic impact of tumor cell detection in the bone marrow of primary breast cancer patients. Clin Cancer Res. 2001;7:4102–4108
  22. Vanhelleputte P, Nijs K, Delforge M, Evers G, Vanderschueren S. Pain during bone marrow aspiration: prevalence and prevention. J Pain Symptom Manage. 2003;26:860–866
  23. Wiedswang G, Borgen E, Karesen R, Kvalheim G, Nesland JM, Qvist H, et al. Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer. J Clin Oncol. 2003;21:3469–3478
  24. Wiedswang G, Borgen E, Karesen R, Qvist H, Janbu J, Kvalheim G, et al. Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavourable clinical outcome. Clin Cancer Res. 2004;10:5342–5348
  25. Yanbaeva DC, Dentener MA, Creutzberg EC, Wesseling G, Wouters EFM. Systemic effects of smoking. Chest. 2007;131:1557–1566

PII: S0960-9776(10)00157-8

doi: 10.1016/j.breast.2010.06.007

The Breast
Volume 20, Issue 1 , Pages 62-65 , February 2011

Article Tools

* Image Usage & Resolution